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Endocrine Abstracts

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ea0099p584 | Late-Breaking | ECE2024

Long-term bone health in women with a premenopausal risk-reducing salpingo-oophorectomy (RRSO) compared with women who underwent

Beekman Maarten , Terra Lara , Stuursma Anniek , Heemskerk-Gerritsen Bernadette , van Beurden Marc , van Doorn Lena , van Dorst Eleonora , de Hullu Joanne , Mom Stijn , Roeters van Lennep Jeanine , Gaarenstroom Katja , Korse Tiny , de Keizer Bart , Mitea Cristina , Slart Riemer , Miranda Snoeren , Stokkel Marcel , Verberne Hein , van Asperen Christi , Ausems Margreet , Berger Lieke , de Bock Truuske , Margriet Collee , van Engelen Klaartje , van der Kolk Lizet , Wevers Marijke , Gomez Garcia Encarna , Hooning Maartje , Maas Angela , Mourits Marian , van Leeuwen Flora , Zillikens Carola

Introduction: To prevent ovarian cancer, BRCA1/2 germline pathogenic variant carriers are recommended to undergo premenopausal risk-reducing salpingo-oophorectomy (RRSO). Premenopausal RRSO leads to immediate surgical menopause, which has been associated with an acute phase of rapid bone loss. However, data on long-term effects is scarce and inconclusive. Therefore, we investigated the long-term impact of premenopausal RRSO on bone mineral density (BMD).<p class="...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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